Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50011074
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50417275(CHEMBL1271939)
Affinity DataIC50: 10nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50417277(CHEMBL1269249)
Affinity DataIC50: 10nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50417267(CHEMBL1271768)
Affinity DataIC50: 16nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50417265(CHEMBL1271708)
Affinity DataIC50: 25nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544690(CHEMBL4647719)
Affinity DataIC50: 100nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataIC50: 119nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544693(CHEMBL4635968)
Affinity DataIC50: 200nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544690(CHEMBL4647719)
Affinity DataIC50: 218nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544696(CHEMBL4642922)
Affinity DataIC50: 229nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544694(CHEMBL4648310)
Affinity DataIC50: 244nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544691(CHEMBL4635391)
Affinity DataIC50: 256nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataIC50: 332nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544691(CHEMBL4635391)
Affinity DataIC50: 384nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544692(CHEMBL4638071)
Affinity DataIC50: 415nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544693(CHEMBL4635968)
Affinity DataIC50: 422nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544697(CHEMBL2218759)
Affinity DataIC50: 474nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544694(CHEMBL4648310)
Affinity DataIC50: 575nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544696(CHEMBL4642922)
Affinity DataIC50: 720nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544695(CHEMBL4648902)
Affinity DataIC50: 813nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544697(CHEMBL2218759)
Affinity DataIC50: 862nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544705(CHEMBL4641636)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544695(CHEMBL4648902)
Affinity DataIC50: 1.25E+3nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544692(CHEMBL4638071)
Affinity DataIC50: 2.39E+3nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544698(CHEMBL4636913)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544699(CHEMBL4645488)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544704(CHEMBL4633098)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544703(CHEMBL4637457)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544702(CHEMBL4639445)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544700(CHEMBL4639608)
Affinity DataIC50: 6.95E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544701(CHEMBL4632746)
Affinity DataIC50: 9.56E+3nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544706(CHEMBL4644334)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544699(CHEMBL4645488)
Affinity DataIC50: 1.51E+4nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544690(CHEMBL4647719)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544691(CHEMBL4635391)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544693(CHEMBL4635968)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544694(CHEMBL4648310)
Affinity DataKi:  118nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544696(CHEMBL4642922)
Affinity DataKi:  147nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544697(CHEMBL2218759)
Affinity DataKi:  176nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544695(CHEMBL4648902)
Affinity DataKi:  256nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544692(CHEMBL4638071)
Affinity DataKi:  489nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50544699(CHEMBL4645488)
Affinity DataKi:  3.11E+3nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed