Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50009279
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526787(CHEMBL4437966)
Affinity DataIC50: 80nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526787(CHEMBL4437966)
Affinity DataIC50: 90nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526786(CHEMBL4591618)
Affinity DataIC50: 410nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526787(CHEMBL4437966)
Affinity DataIC50: 500nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526787(CHEMBL4437966)
Affinity DataIC50: 510nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526786(CHEMBL4591618)
Affinity DataIC50: 590nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526786(CHEMBL4591618)
Affinity DataIC50: 650nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526786(CHEMBL4591618)
Affinity DataIC50: 770nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using calcein-AM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50061306(CHEMBL1205 | Viracept | (3S,4aS,8aS)-2-[(2R,3R)-2-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50061306(CHEMBL1205 | Viracept | (3S,4aS,8aS)-2-[(2R,3R)-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50061306(CHEMBL1205 | Viracept | (3S,4aS,8aS)-2-[(2R,3R)-2-...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50061306(CHEMBL1205 | Viracept | (3S,4aS,8aS)-2-[(2R,3R)-2-...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using calcein-AM as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of P-gp in human 12D7-MDR cells using NBD-Aba as substrate after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed