Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50006713
TargetEpidermal growth factor receptor(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 0.769nMAssay Description:Inhibition of EGFR (unknown origin) using TK substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50502665(CHEMBL4520064)
Affinity DataIC50: 46nMAssay Description:Inhibition of VEGFR2 (unknown origin) using TK substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 141nMAssay Description:Inhibition of VEGFR2 (unknown origin) using TK substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50502665(CHEMBL4520064)
Affinity DataIC50: 385nMAssay Description:Inhibition of EGFR (unknown origin) using TK substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 583nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using TK substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50502665(CHEMBL4520064)
Affinity DataIC50: 674nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using TK substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed