Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50006712
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50502662(CHEMBL4471147)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human GST tagged GGPPs expressed in Escherichia coli BL21 gold cells using [14C] IPP and FPP as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50502663(CHEMBL4476604)
Affinity DataIC50: 670nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50502664(CHEMBL4453988)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50502663(CHEMBL4476604)
Affinity DataIC50: 8.14E+4nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50502664(CHEMBL4453988)
Affinity DataIC50: 9.12E+4nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed