Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50009115
TargetMu-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525575(CHEMBL4451045)
Affinity DataEC50: >10nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50517919(CHEMBL4445059)
Affinity DataEC50:  587nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525575(CHEMBL4451045)
Affinity DataEC50:  5nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525575(CHEMBL4451045)
Affinity DataEC50:  60nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525578(CHEMBL4516807)
Affinity DataEC50: >10nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50517888(CHEMBL4442842)
Affinity DataEC50:  43nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15790(CHEMBL42908 | Hydroxyethylene-Based Peptidomimetic...)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE-1 (unknown origin) using MPBC125-fused APP as substrate incubated for 1 to 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525576(CHEMBL4556276)
Affinity DataIC50: 120nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human HLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  6.90nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525579(CHEMBL4514048)
Affinity DataKi:  43nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036093(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  101nMAssay Description:Inhibition of human HLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525577(CHEMBL4531577)
Affinity DataKi:  157nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed