Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50008238
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human D2S receptor expressed in CHOK1 cells assessed as inhibition of forskolin induced cAMP production incubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataIC50: 0.708nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataIC50: 0.720nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517002(CHEMBL4554558)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517002(CHEMBL4554558)
Affinity DataIC50: 2.42E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataIC50: 2.62E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataIC50: 2.63E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataIC50: 7.94E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataIC50: 7.98E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516999(CHEMBL4463034)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50154709(TCMDC-139048 | 3-(1-Benzyl-1,2,3,6-tetrahydro-pyri...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517002(CHEMBL4554558)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517010(CHEMBL4565126)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517011(CHEMBL4578143)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516995(CHEMBL4460564)
Affinity DataKi:  112nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516999(CHEMBL4463034)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50231640(CHEMBL285157 | TCMDC-123457)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517006(CHEMBL4466356)
Affinity DataKi:  132nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517005(CHEMBL4449936)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516995(CHEMBL4460564)
Affinity DataKi:  135nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50154709(TCMDC-139048 | 3-(1-Benzyl-1,2,3,6-tetrahydro-pyri...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516994(CHEMBL4527257)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516996(CHEMBL4444351)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517001(CHEMBL4543263)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516999(CHEMBL4463034)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor expressed in commercial cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517005(CHEMBL4449936)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517009(CHEMBL4454000)
Affinity DataKi:  151nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516996(CHEMBL4444351)
Affinity DataKi:  157nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517011(CHEMBL4578143)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516997(CHEMBL4548632)
Affinity DataKi:  165nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516994(CHEMBL4527257)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517002(CHEMBL4554558)
Affinity DataKi:  171nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517000(CHEMBL4521477)
Affinity DataKi:  173nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517006(CHEMBL4466356)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517001(CHEMBL4543263)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517004(CHEMBL4457881)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517003(CHEMBL4558444)
Affinity DataKi:  214nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517009(CHEMBL4454000)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517010(CHEMBL4565126)
Affinity DataKi:  243nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataKi:  243nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517000(CHEMBL4521477)
Affinity DataKi:  257nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517007(CHEMBL4460839)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517007(CHEMBL4460839)
Affinity DataKi:  299nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50517002(CHEMBL4554558)
Affinity DataKi:  305nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
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