Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50007371
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataIC50: 31.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508928(CHEMBL4436660)
Affinity DataIC50: 49.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508929(CHEMBL4515750)
Affinity DataIC50: 61.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508927(CHEMBL4543845)
Affinity DataIC50: 81.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508925(CHEMBL4437261)
Affinity DataIC50: 94.9nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508926(CHEMBL4446041)
Affinity DataIC50: 128nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 144nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)