Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50007775
TargetSterol O-acyltransferase 1(Chinese hamster)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50242257(2-(1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8,8a-octahydr...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50242257(2-(1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8,8a-octahydr...)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Green monkey)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50242257(2-(1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8,8a-octahydr...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Green monkey)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50196069(CHEMBL3965313)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50196069(CHEMBL3965313)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Chinese hamster)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50196069(CHEMBL3965313)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed