Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50008731
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM18073(L-[2,3,4,5,6-3H]phenylalanine | (2S)-2-amino-3-phe...)
Affinity DataIC50: 6.90E+4nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50463186(CHEMBL4242404)
Affinity DataIC50: 6.90E+4nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50463209(CHEMBL4249170)
Affinity DataIC50: 1.00E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM181118(US9138393, Histidine | US9144538, Histidine)
Affinity DataIC50: 1.10E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50463195(CHEMBL4243343)
Affinity DataIC50: 1.60E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM21974((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...)
Affinity DataIC50: 1.60E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50521753(CHEMBL4464816)
Affinity DataIC50: 1.60E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50463190(CHEMBL4240267)
Affinity DataIC50: 1.70E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50463197(CHEBI:50599 | CHEMBL1233327)
Affinity DataIC50: 1.90E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50521754(CHEMBL4559029)
Affinity DataIC50: 3.40E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50521751(CHEMBL4586342)
Affinity DataIC50: 4.40E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50521749(CHEMBL4448346)
Affinity DataIC50: 1.00E+6nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50521750(CHEMBL4569744)
Affinity DataIC50: 1.00E+6nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of Nebraska At Kearney

Curated by ChEMBL
LigandPNGBDBM50521752(CHEMBL4587818)
Affinity DataIC50: 1.00E+6nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed