Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50008027
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM109086(US8604016, 670 | US9938267, Cmpd ID 670 | US107935...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514979(CHEMBL4457936)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514986(CHEMBL4437956)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514985(CHEMBL4573635)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514975(CHEMBL4473143)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50150109(CHEMBL3770355)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514977(CHEMBL4461749)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514982(CHEMBL4469711)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514978(CHEMBL4451434)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 51nMAssay Description:Inhibition of GLS1 GAC isoform (unknown origin) using glutamine as substrate preincubated for 15 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108464(US8604016, 21 | US9938267, Cmpd ID 21)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50172138(CHEMBL3808443 | US10040788, Example 1(a) | US10294...)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514990(CHEMBL4448931)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514974(CHEMBL4472367)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514989(CHEMBL4444363)
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514991(CHEMBL4594003)
Affinity DataIC50: 114nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US8604016, 1 | US9938267, Cmpd ID ...)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50: 202nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514983(CHEMBL4447951)
Affinity DataIC50: 207nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514988(CHEMBL4548654)
Affinity DataIC50: 244nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50: 347nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514984(CHEMBL4534437)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514987(CHEMBL4570299)
Affinity DataIC50: 873nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514976(CHEMBL4458193)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514981(CHEMBL4434859)
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of 5HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50172138(CHEMBL3808443 | US10040788, Example 1(a) | US10294...)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514976(CHEMBL4458193)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514987(CHEMBL4570299)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514978(CHEMBL4451434)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514989(CHEMBL4444363)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514990(CHEMBL4448931)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514983(CHEMBL4447951)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514982(CHEMBL4469711)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108464(US8604016, 21 | US9938267, Cmpd ID 21)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514975(CHEMBL4473143)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50150109(CHEMBL3770355)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514986(CHEMBL4437956)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514977(CHEMBL4461749)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US8604016, 1 | US9938267, Cmpd ID ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514974(CHEMBL4472367)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of OPRM (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of dopamine transporter (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400(US10040788, Example 2(a) | (2S)-2-Methoxy-2-phenyl...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of NK1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed