Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50008828
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522762(CHEMBL4475087)
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522755(CHEMBL4528755)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522758(CHEMBL4473832)
Affinity DataIC50: 4.59E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522753(CHEMBL4514758)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522761(CHEMBL4465327)
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522754(CHEMBL4453336)
Affinity DataIC50: 5.88E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522759(CHEMBL4461708)
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522757(CHEMBL4458937)
Affinity DataIC50: 8.84E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522760(CHEMBL4471983)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
North China Pharmaceutical Group

Curated by ChEMBL
LigandPNGBDBM50522756(CHEMBL4532631)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 15 mins followed by NAD+ addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed