Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50009084
TargetEstrogen receptor(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525253(CHEMBL4518283)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of ERalpha in human MCF7 cells after 36 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50118551(Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl e...)
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50118567(Sulfamic acid 2-nonyl-4-oxo-4H-chromen-6-yl ester ...)
Affinity DataIC50: 0.0890nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525257(CHEMBL4520995)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525260(CHEMBL4465348)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50121105(CHEMBL3622055)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50118560(Sulfamic acid 2-adamantan-1-yl-4-oxo-4H-thiochrome...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of sulfatase (unknown origin) using 4-MUS as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50369431(CHEMBL1627878)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50047259(4-(1-(1H-imidazol-1-yl)vinyl)benzonitrile | 4-(1-I...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM10020(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50121078(CHEMBL3622063)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM10019((2-chloro-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-y...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525260(CHEMBL4465348)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50041611((E)-3-[4-((Z)-1,2-Diphenyl-but-1-enyl)-phenyl]-acr...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Fluormone-ES2 binding affinity to ERalpha (unknown origin) after 2 hrs by fluorescent polarization based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50121196(CHEMBL3622029)
Affinity DataIC50: 3nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525263(CHEMBL4444074)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50369431(CHEMBL1627878)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525261(CHEMBL4436482)
Affinity DataIC50: 14nMAssay Description:Inhibition of sulfatase (unknown origin) expressed in HEK293 cells using [3H]DHEAS as substrate after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM10019((2-chloro-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-y...)
Affinity DataIC50: 20nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50363594(CHEMBL1627429)
Affinity DataIC50: 24nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50121078(CHEMBL3622063)
Affinity DataIC50: 26nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50: 28nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525266(CHEMBL4547986)
Affinity DataIC50: 30nMAssay Description:Inhibition of ERalpha (unknown origin) after 18 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50121058(CHEMBL275331)
Affinity DataIC50: 30nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM10020(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 39nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50097366(4-((1H-imidazol-1-yl)methyl)-1-nitro-4aH-xanthen-9...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human aromatase using [1beta,2beta3H]-]testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525256(CHEMBL4540847)
Affinity DataIC50: 41nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50084948(GW7604 | CHEMBL195515)
Affinity DataIC50: 43nMAssay Description:Inhibition of Fluormone-ES2 binding affinity to ERalpha (unknown origin) after 2 hrs by fluorescent polarization based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50097373(4-Imidazol-1-ylmethyl-9-oxo-9H-xanthene-1-carbonit...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human aromatase using [1beta,2beta3H]-]testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525261(CHEMBL4436482)
Affinity DataIC50: 46nMAssay Description:Inhibition of sulfatase (unknown origin) expressed in HEK293 cells using [3H]E1S as substrate after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525258(CHEMBL4529949)
Affinity DataIC50: 56nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525270(CHEMBL4435618)
Affinity DataIC50: 72nMAssay Description:Inhibition of human placental microsome sulfatase using estrone sulfate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525254(CHEMBL4475271)
Affinity DataIC50: 80nMAssay Description:Inhibition of Estrogen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525267(CHEMBL4583456)
Affinity DataIC50: 91nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525252(CHEMBL1997442)
Affinity DataIC50: 100nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate after 15 mins in presence of NADPH by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525254(CHEMBL4475271)
Affinity DataIC50: 100nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50151136(2-Adamantan-1-yl-4-oxo-4H-thiochromene-6-carbonitr...)
Affinity DataIC50: 180nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50: 205nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM9454(7-(benzyloxy)-3-phenyl-2-[(pyridin-4-ylmethyl)sulf...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human placental microsome aromatase using [1beta[3H]]androst-4-ene-3,17-dione as substrate after 15 mins in presence of NADPH by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50025055(3-(4-Amino-phenyl)-3-(3-methyl-butyl)-piperidine-2...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]-]testosterone as substrate measured up to 21 mins in presence of NADPH by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50525262(CHEMBL4444347)
Affinity DataIC50: 460nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 20 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50025062(3-(4-Amino-phenyl)-3-(1-methyl-butyl)-piperidine-2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]-]testosterone as substrate measured up to 21 mins in presence of NADPH by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50111269(7-Methoxy-2-phenyl-3-pyridin-4-ylmethylene-chroman...)
Affinity DataIC50: 620nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50111268(2-Phenyl-3-pyridin-4-ylmethylene-chroman-4-one | C...)
Affinity DataIC50: 800nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50025065(3-(4-Amino-phenyl)-3-(2-methyl-butyl)-piperidine-2...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]-]testosterone as substrate measured up to 21 mins in presence of NADPH by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Indian Institute of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50025056(3-(4-Amino-phenyl)-3-pentyl-piperidine-2,6-dione |...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]-]testosterone as substrate measured up to 21 mins in presence of NADPH by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 72 total ) | Next | Last >>
Jump to: