Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50008816
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM32378(adenosine-derived inhibitor (Grp78), 13 | adenosin...)
Affinity DataIC50: 800nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM31712(SMR000058356 | MLS000028433 | cid_3598 | HEXACHLOR...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM31712(SMR000058356 | MLS000028433 | cid_3598 | HEXACHLOR...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM31712(SMR000058356 | MLS000028433 | cid_3598 | HEXACHLOR...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM430653(Oxyclozanide)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50522651(CHEMBL460648)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50522652(CHEMBL3182523)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50522653(CHEBI:34207 | 2-(2-Hydroxybenzyl)Phenol | CHEMBL14...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50303912(4-chloro-2-(5-chloro-2-hydroxybenzyl)phenol | Dich...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum chaperone BiP(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed