Compile Data Set for Download or QSAR
Report error Found 95 Enz. Inhib. hit(s) with all data for entry = 50007835
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513177(CHEMBL4444602)
Affinity DataIC50: 13nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420857(US10479784, Compound IIA-10 | US10961232, Compound...)
Affinity DataIC50: 76nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513173(CHEMBL4566104)
Affinity DataIC50: 130nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420860(US10479784, Compound IIA-13 | US10961232, Compound...)
Affinity DataIC50: 130nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513176(CHEMBL4448538)
Affinity DataIC50: 210nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513172(CHEMBL4467848)
Affinity DataIC50: 300nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420609(US10479784, Compound IA-116 | US10961232, Compound...)
Affinity DataIC50: 410nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513175(CHEMBL4530813)
Affinity DataIC50: 800nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50341747(3-amino-6-(4-(isopropylsulfonyl)phenyl)-N-phenylpy...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513181(CHEMBL4440048)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513178(CHEMBL4434665)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513174(CHEMBL4445532)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513180(CHEMBL4593939)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50437436(CHEMBL2409216 | US8841450, I-1)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM132734(US8846917, I-1)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513179(CHEMBL4558884)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420852(US10479784, Compound IIA-5 | US10961232, Compound ...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513177(CHEMBL4444602)
Affinity DataKi:  0.140nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  0.165nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420857(US10479784, Compound IIA-10 | US10961232, Compound...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420852(US10479784, Compound IIA-5 | US10961232, Compound ...)
Affinity DataKi:  0.270nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513173(CHEMBL4566104)
Affinity DataKi:  0.530nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513176(CHEMBL4448538)
Affinity DataKi:  0.75nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420609(US10479784, Compound IA-116 | US10961232, Compound...)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513181(CHEMBL4440048)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513178(CHEMBL4434665)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513172(CHEMBL4467848)
Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513175(CHEMBL4530813)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420860(US10479784, Compound IIA-13 | US10961232, Compound...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50341747(3-amino-6-(4-(isopropylsulfonyl)phenyl)-N-phenylpy...)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513179(CHEMBL4558884)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513174(CHEMBL4445532)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM132734(US8846917, I-1)
Affinity DataKi:  6nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  8nMAssay Description:ATP competitive inhibition of human Flt4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  15nMAssay Description:ATP competitive inhibition of human MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  18nMAssay Description:ATP competitive inhibition of human Flt3 D835Y mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513182(CHEMBL4473876)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420609(US10479784, Compound IA-116 | US10961232, Compound...)
Affinity DataKi:  22nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50513180(CHEMBL4593939)
Affinity DataKi:  26nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  26nMAssay Description:ATP competitive inhibition of human DYRK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  30nMAssay Description:ATP competitive inhibition of human MerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  33nMAssay Description:ATP competitive inhibition of human GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  39nMAssay Description:ATP competitive inhibition of human c-Kit D816H mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(US10208027, Compound II-1 | US10208027, Compound I...)
Affinity DataKi:  44nMAssay Description:Inhibition of full-length ATM (unknown origin) using DPSVEPPLSQETFSDKKK peptide as substrate measured after 24 hrs in presence of [gamma-33P] ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM420857(US10479784, Compound IIA-10 | US10961232, Compound...)
Affinity DataKi:  47nMAssay Description:Inhibition of full-length ATM (unknown origin) using DPSVEPPLSQETFSDKKK peptide as substrate measured after 24 hrs in presence of [gamma-33P] ATP by ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 95 total ) | Next | Last >>
Jump to: