Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50010126
TargetP2X purinoceptor 3(Mouse)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535408(CHEMBL4462568)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Mouse)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Mouse)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535410(CHEMBL4525343)
Affinity DataIC50: 83nMAssay Description:Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Mouse)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535415(CHEMBL4463578)
Affinity DataIC50: 127nMAssay Description:Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Mouse)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535409(CHEMBL4456926)
Affinity DataIC50: 211nMAssay Description:Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 611nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535410(CHEMBL4525343)
Affinity DataIC50: 883nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Mouse)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535413(CHEMBL4561510)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535408(CHEMBL4462568)
Affinity DataIC50: 4.11E+3nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535409(CHEMBL4456926)
Affinity DataIC50: 5.83E+3nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535410(CHEMBL4525343)
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 8.53E+3nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535412(CHEMBL4570607)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535412(CHEMBL4570607)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535409(CHEMBL4456926)
Affinity DataIC50: 1.24E+4nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535415(CHEMBL4463578)
Affinity DataIC50: 1.75E+4nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535410(CHEMBL4525343)
Affinity DataIC50: 2.96E+4nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535412(CHEMBL4570607)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535411(CHEMBL4440260)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535412(CHEMBL4570607)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535408(CHEMBL4462568)
Affinity DataIC50: 4.11E+4nMAssay Description:Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535408(CHEMBL4462568)
Affinity DataIC50: 4.80E+4nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535409(CHEMBL4456926)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535411(CHEMBL4440260)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535410(CHEMBL4525343)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535415(CHEMBL4463578)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535410(CHEMBL4525343)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535415(CHEMBL4463578)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535415(CHEMBL4463578)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535415(CHEMBL4463578)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535409(CHEMBL4456926)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535413(CHEMBL4561510)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535408(CHEMBL4462568)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535413(CHEMBL4561510)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535411(CHEMBL4440260)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535413(CHEMBL4561510)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535413(CHEMBL4561510)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535411(CHEMBL4440260)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535413(CHEMBL4561510)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535411(CHEMBL4440260)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535408(CHEMBL4462568)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535409(CHEMBL4456926)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X1R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed