Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50010305
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50256322(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537285(CHEMBL4570327)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537288(CHEMBL4552537)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50256322(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537286(CHEMBL4483646)
Affinity DataIC50: 7nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537287(CHEMBL4521642)
Affinity DataIC50: 7nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537290(CHEMBL4588109)
Affinity DataIC50: 9nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537285(CHEMBL4570327)
Affinity DataIC50: 16nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537289(CHEMBL4559633)
Affinity DataIC50: 22nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537283(CHEMBL4513652)
Affinity DataIC50: 24nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537287(CHEMBL4521642)
Affinity DataIC50: 30nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537288(CHEMBL4552537)
Affinity DataIC50: 68nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537286(CHEMBL4483646)
Affinity DataIC50: 104nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537289(CHEMBL4559633)
Affinity DataIC50: 135nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537283(CHEMBL4513652)
Affinity DataIC50: 169nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537290(CHEMBL4588109)
Affinity DataIC50: 170nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537284(CHEMBL4547623)
Affinity DataIC50: 172nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537284(CHEMBL4547623)
Affinity DataIC50: 523nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed