Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50002413
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022130(3-(2-Cyclopropyl-3-imidazol-1-ylmethyl-indol-1-yl)...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022118(3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-p...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022117(1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL11...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022131(3-(3-Imidazol-1-ylmethyl-6-trifluoromethyl-indol-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022129(3-(5-Bromo-3-imidazol-1-ylmethyl-indol-1-yl)-propi...)
Affinity DataIC50: 12nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole(UK-347...)
Affinity DataIC50: 15nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: 19nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022119(3-(5-Chloro-3-imidazol-1-ylmethyl-indol-1-yl)-prop...)
Affinity DataIC50: 21nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50: 25nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: 28nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022126((3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acid | C...)
Affinity DataIC50: 30nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022127(3-(3-Imidazol-1-ylmethyl-5-methyl-indol-1-yl)-prop...)
Affinity DataIC50: 42nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022122(3-(3-Imidazol-1-ylmethyl-5-methoxy-indol-1-yl)-pro...)
Affinity DataIC50: 43nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022123(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-acry...)
Affinity DataIC50: 70nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022125(3-(5-Dimethylamino-3-imidazol-1-ylmethyl-indol-1-y...)
Affinity DataIC50: 82nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole(UK-347...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022132(5-Chloro-3-imidazol-1-ylmethyl-1H-indole | CHEMBL1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022128(3-Imidazol-1-ylmethyl-6-trifluoromethyl-1H-indole ...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50022117(1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL11...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50022118(3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022130(3-(2-Cyclopropyl-3-imidazol-1-ylmethyl-indol-1-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022129(3-(5-Bromo-3-imidazol-1-ylmethyl-indol-1-yl)-propi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022123(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-acry...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50022117(1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL11...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50022126((3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acid | C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole(UK-347...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022118(3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022127(3-(3-Imidazol-1-ylmethyl-5-methyl-indol-1-yl)-prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022131(3-(3-Imidazol-1-ylmethyl-6-trifluoromethyl-indol-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022125(3-(5-Dimethylamino-3-imidazol-1-ylmethyl-indol-1-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole(UK-347...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022126((3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acid | C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022122(3-(3-Imidazol-1-ylmethyl-5-methoxy-indol-1-yl)-pro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022119(3-(5-Chloro-3-imidazol-1-ylmethyl-indol-1-yl)-prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50: 6.50E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed