Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50010427
TargetSolute carrier family 22 member 12(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50093473(Arhalofenate | CB-102 | JNJ-39659100 | M-102 | MBX...)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(RDEA3170 | US10100016, Verinurad (RDEA3170) | CAS ...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 220nMAssay Description:Inhibition of URAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Yes(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of URAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 11(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of OAT4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of OAT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50241408(CHEMBL252642 | (2S)-liquiritigenin | Liquiritigeni...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of OAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 11(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 5.49E+4nMAssay Description:Inhibition of OAT4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50: 2.74E+5nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM22109(CHEMBL1213653 | 7-{[(3R,4R)-3-hydroxy-4-(hydroxyme...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of xanthine dehydrogenase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50267750(CHEMBL1078685)
Affinity DataKi:  5.70nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50538736(CHEMBL4640580)
Affinity DataKi:  57nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKi:  472nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataKi:  700nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKi:  2.38E+3nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50538736(CHEMBL4640580)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human OAT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM7462(cid_5280863 | CHEMBL150 | 3,5,7-trihydroxy-2-(4-hy...)
Affinity DataKi:  6.77E+3nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50538736(CHEMBL4640580)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibition of human OAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataKi:  7.90E+3nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed