Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50009595
TargetDual specificity protein kinase CLK2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human CLK2 in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human CLK2 in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant human DYRK1B in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant human DYRK1B in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human DYRK1A in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human DYRK1A in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM165207(US9062043, Table 13, Compound 1 | US9062043, Table...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM165207(US9062043, Table 13, Compound 1 | US9062043, Table...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha V73A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha V73A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha K74A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha K74A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530336(CHEMBL4462082)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530332(CHEMBL4439686)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CK2alpha (unknown origin) incubated for 40 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530332(CHEMBL4439686)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CK2alpha (unknown origin) incubated for 40 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530336(CHEMBL4462082)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha H160A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha H160A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530338(CHEMBL1621959)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530338(CHEMBL1621959)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha K77A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha K77A mutant in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530318(CHEMBL4526405)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530318(CHEMBL4526405)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530316(CHEMBL4455046)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530316(CHEMBL4455046)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530337(CHEMBL4557432)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530337(CHEMBL4557432)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataKi:  700nMAssay Description:Mixed-type inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530325(CHEMBL4458300)
Affinity DataKi:  700nMAssay Description:Mixed-type inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530338(CHEMBL1621959)
Affinity DataKi:  1.10E+3nMAssay Description:Mixed-type inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530338(CHEMBL1621959)
Affinity DataKi:  1.10E+3nMAssay Description:Mixed-type inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530336(CHEMBL4462082)
Affinity DataKi:  1.60E+3nMAssay Description:Mixed-type inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50530336(CHEMBL4462082)
Affinity DataKi:  1.60E+3nMAssay Description:Mixed-type inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed