Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50009377
TargetBeta-2 adrenergic receptor(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50084437(Batefenterol | GSK961081 | GSK961081A | TD-5959)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50528210(Azd 8871 | Azd-8871 | Azd8871 | LAS-191351 | LAS19...)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50528212(CHEMBL4465556)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM221902(US9315463, 12)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM221902(US9315463, 12)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50084437(Batefenterol | GSK961081 | GSK961081A | TD-5959)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50528212(CHEMBL4465556)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50528210(Azd 8871 | Azd-8871 | Azd8871 | LAS-191351 | LAS19...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50528211(CHEMBL4565954)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE4B2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50528211(CHEMBL4565954)
Affinity DataIC50: 11nMAssay Description:Inhibition of beta2 adrenoceptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50180609(3-[4-(4-Chlorophenylethynyl)benzoyl]nonanoic acid ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMacrophage metalloelastase(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50299051(N-Hydroxy-2-{2-[4-(4-methoxy-phenoxy)benzenesulfon...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by high throughput automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50120437(CHEMBL3617973)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of human Neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital

Curated by ChEMBL
LigandPNGBDBM50528213(CHEMBL4560341)
Affinity DataKi:  6.20nMAssay Description:Inhibition of M2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed