Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50009182
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525968(CHEMBL4457145)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525969(CHEMBL4529443)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525969(CHEMBL4529443)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525968(CHEMBL4457145)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525962(CHEMBL4464314)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525964(CHEMBL4546082)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525964(CHEMBL4546082)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525962(CHEMBL4464314)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525971(CHEMBL4574253)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515446(CHEMBL4441152)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515446(CHEMBL4441152)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525966(CHEMBL4552641)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525963(CHEMBL4582194)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525967(CHEMBL4538007)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525970(CHEMBL4450585)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50: 2nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525970(CHEMBL4450585)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of 17beta-HSD2 in human using MDA-MB-231 cells using [3H]-E2 as substrate after 6 hrs by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525972(CHEMBL4459887)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525971(CHEMBL4574253)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525966(CHEMBL4552641)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525962(CHEMBL4464314)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525963(CHEMBL4582194)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50: 6nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525964(CHEMBL4546082)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525972(CHEMBL4459887)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525973(CHEMBL4461477)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525973(CHEMBL4461477)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525969(CHEMBL4529443)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525965(CHEMBL4519897)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525967(CHEMBL4538007)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525967(CHEMBL4538007)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525968(CHEMBL4457145)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525966(CHEMBL4552641)
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525970(CHEMBL4450585)
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525965(CHEMBL4519897)
Affinity DataIC50: 14nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525972(CHEMBL4459887)
Affinity DataIC50: 16nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525971(CHEMBL4574253)
Affinity DataIC50: 20nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126982(CHEMBL3629438)
Affinity DataIC50: 21nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50: 25nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515446(CHEMBL4441152)
Affinity DataIC50: 27nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525963(CHEMBL4582194)
Affinity DataIC50: 31nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525973(CHEMBL4461477)
Affinity DataIC50: 82nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126982(CHEMBL3629438)
Affinity DataIC50: 111nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525961(CHEMBL4459492)
Affinity DataIC50: 231nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525965(CHEMBL4519897)
Affinity DataIC50: 304nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525961(CHEMBL4459492)
Affinity DataIC50: 306nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of recombinant mouse 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed