Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50009744
TargetTranscriptional enhancer factor TEF-1(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to TEAD1 (194 to 411 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-4(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Gal4-fused TEAD2 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of Gal4-fused TEAD4 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Gal4-fused TEAD1 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of Gal4-fused TEAD3 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50531837(CHEMBL4578591)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of NL-tagged YAP (unknown origin) interaction with myc-tagged human TEAD1 preincubated for 1 hr followed by NL-tagged YAP addition by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed