Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50006841
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503761(CHEMBL4514232)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503773(CHEMBL4474660)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503774(CHEMBL4444783)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503773(CHEMBL4474660)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503772(CHEMBL4579760)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503772(CHEMBL4579760)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503767(CHEMBL4547387)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503770(CHEMBL4571646)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503766(CHEMBL4470607)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503761(CHEMBL4514232)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503767(CHEMBL4547387)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503769(CHEMBL4541853)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503772(CHEMBL4579760)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503763(CHEMBL4441141)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503771(CHEMBL4476231)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM89011(cid_676300 | MLS001360579 | SMR001223867 | 4'-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM89011(cid_676300 | MLS001360579 | SMR001223867 | 4'-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503766(CHEMBL4470607)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503768(CHEMBL4573324)
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503769(CHEMBL4541853)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503761(CHEMBL4514232)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503763(CHEMBL4441141)
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503762(CHEMBL4436010)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503773(CHEMBL4474660)
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503768(CHEMBL4573324)
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503764(CHEMBL4464279)
Affinity DataIC50: 135nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503771(CHEMBL4476231)
Affinity DataIC50: 146nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503770(CHEMBL4571646)
Affinity DataIC50: 216nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503770(CHEMBL4571646)
Affinity DataIC50: 433nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503774(CHEMBL4444783)
Affinity DataIC50: 525nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503765(CHEMBL1223487)
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503774(CHEMBL4444783)
Affinity DataIC50: 667nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503771(CHEMBL4476231)
Affinity DataIC50: 689nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM89011(cid_676300 | MLS001360579 | SMR001223867 | 4'-...)
Affinity DataIC50: 909nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503767(CHEMBL4547387)
Affinity DataIC50: 991nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503764(CHEMBL4464279)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate after 15 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503764(CHEMBL4464279)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate after 30 mins in presence of NADPH by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed