Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50007188
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507212(CHEMBL4585990)
Affinity DataIC50: 13nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507208(CHEMBL4526050)
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507211(CHEMBL4444843)
Affinity DataIC50: 29nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507210(CHEMBL4454706)
Affinity DataIC50: 40nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507213(CHEMBL4529710)
Affinity DataIC50: 51nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507216(CHEMBL4559904)
Affinity DataIC50: 84nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507209(CHEMBL4537101)
Affinity DataIC50: 91nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507215(CHEMBL4562793)
Affinity DataIC50: 94nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507220(CHEMBL4578844)
Affinity DataIC50: 133nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507217(CHEMBL4541090)
Affinity DataIC50: 261nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507219(CHEMBL4540355)
Affinity DataIC50: 275nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507218(CHEMBL4583738)
Affinity DataIC50: 559nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507214(CHEMBL4567394)
Affinity DataIC50: 716nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507212(CHEMBL4585990)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507211(CHEMBL4444843)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507209(CHEMBL4537101)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507208(CHEMBL4526050)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM84950(CAS_183782 | NSC_183782 | RS 67333)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  10nMAssay Description:Agonist activity at 5-HT4R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  16nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507215(CHEMBL4562793)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507211(CHEMBL4444843)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507213(CHEMBL4529710)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507209(CHEMBL4537101)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507214(CHEMBL4567394)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507210(CHEMBL4454706)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507208(CHEMBL4526050)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507212(CHEMBL4585990)
Affinity DataKi:  169nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed