Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50007228
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 556nMAssay Description:Inhibition of PD1/PDL1 interaction in human jurkat cells co-expressing TCR promoter assessed as TCR activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.38E+3nMAssay Description:Binding affinity to human PD1 (34 to 150 residues) expressed in Escherichia coli BL21 (DE3) measured for 120 secs by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.13E+3nMAssay Description:Binding affinity to human PD1 (34 to 150 residues) expressed in Escherichia coli BL21 (DE3) measured for 120 secs by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 9.40E+4nMAssay Description:Binding affinity to biotinylated PDL1 (unknown origin) expressed in Escherichia coli OmpX membrane after 45 mins by SAPE-fluorescence based flow cyto...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 293nMAssay Description:Inhibition of PD1/PDL1 interaction in human jurkat cells co-expressing TCR promoter assessed as TCR activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Inhibition of mouse PDL2 in mouse splenocytes assessed as rescue of splenocyte effector functionMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Inhibition of mouse PDL1 in mouse splenocytes assessed as rescue of splenocyte effector functionMore data for this Ligand-Target Pair
Affinity DataKd: 3.14E+3nMAssay Description:Binding affinity to human PD1 (34 to 150 residues) expressed in Escherichia coli BL21 (DE3) measured for 120 secs by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.39E+3nMAssay Description:Binding affinity to human PD1 (34 to 150 residues) expressed in Escherichia coli BL21 (DE3) measured for 120 secs by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+4nMAssay Description:Binding affinity to Fc-labeled human PDL1 expressed in Escherichia coli by SPR spectroscopyMore data for this Ligand-Target Pair
Affinity DataKd: 510nMAssay Description:Binding affinity to Fc-labeled human PDL1 expressed in Escherichia coli by SPR spectroscopyMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 6.30E+3nMAssay Description:Inhibition of PD1/PDL1 interaction in human jurkat cells co-expressing TCR promoter assessed as TCR activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.13E+3nMAssay Description:Binding affinity to Fc-labeled human PDL1 expressed in Escherichia coli by SPR spectroscopyMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0nMAssay Description:Inhibition of recombinant human PD1 (25 to 167 residues)/human PDL1 (19 to 238 residues) interaction after 40 mins by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of PD1/PDL1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of PD1/PDL1 interaction (unknown origin) after 15 mins by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of PD1/PDL1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Inhibition of PD1/PDL1 interaction (unknown origin) after 15 mins by HTRF assayMore data for this Ligand-Target Pair
