Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50002487
TargetInsulin-degrading enzyme(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459189(CHEMBL4211248)
Affinity DataKd:  22nMAssay Description:Binding affinity to IDE E111Q mutant (unknown origin) using N-terminal FITC-labeled compound after 2 hrs in absence of light at 298 K by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459189(CHEMBL4211248)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459187(CHEMBL4211765)
Affinity DataIC50: 44nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459188(CHEMBL4206878)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459190(CHEMBL4208119)
Affinity DataIC50: 74nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459181(CHEMBL4207403)
Affinity DataIC50: 77nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459180(CHEMBL4203249)
Affinity DataIC50: 86nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459191(CHEMBL4215687)
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459182(CHEMBL4210721)
Affinity DataIC50: 230nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459186(CHEMBL4216209)
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459184(CHEMBL4203477)
Affinity DataIC50: 601nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459183(CHEMBL4208342)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459185(CHEMBL4204003)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50458054(CHEBI:35862 | Albac 50 | Baci-Rx | Baciferm 50 | B...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed