Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50003267
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataKd:  665nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataKd:  220nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50: 6nMAssay Description:Inhibition of microtubule-stimulated Eg5 ATPase activity in human HL-60 cells after 48 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50463316(KF 89617 | KF-89617 | Kf89617 | LY 2523355 | LY-25...)
Affinity DataIC50: 26nMAssay Description:Inhibition of microtubule-stimulated human Eg5 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataIC50: 493nMAssay Description:Inhibition of N-terminal His6-tagged microtubule-stimulated ATPase activity of human Eg5 motor domain (1 to 368 residues) expressed in Escherichia co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataIC50: 580nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50: 740nMAssay Description:Inhibition of N-terminal His6-tagged microtubule-stimulated ATPase activity of human Eg5 motor domain (1 to 368 residues) expressed in Escherichia co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50: 740nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468752(CHEMBL3735751)
Affinity DataIC50: 840nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468759(CHEMBL1391655)
Affinity DataIC50: 950nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of microtubule-stimulated recombinant human Eg5 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468750(CHEMBL3735259)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468758(CHEMBL1369692)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468763(CHEMBL4283187)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468751(CHEMBL4287823)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468754(CHEMBL1565660)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468762(CHEMBL3735499)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468757(CHEMBL4288387)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468760(CHEMBL1373238)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468765(CHEMBL1599833)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468753(CHEMBL1712931)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM90458(SMR000285675 | MLS000693062 | N-(4-ethanoyl-5-meth...)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468749(CHEMBL4279312)
Affinity DataIC50: 4.11E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468761(CHEMBL4283892)
Affinity DataIC50: 4.69E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468764(CHEMBL4288725)
Affinity DataIC50: 5.39E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50468756(CHEMBL4293322)
Affinity DataIC50: 5.99E+4nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed