Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50003250
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468557(CHEMBL4294787)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468570(CHEMBL4290513)
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468565(CHEMBL4277125)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468572(CHEMBL4279170)
Affinity DataIC50: 820nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468557(CHEMBL4294787)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of recombinant human GST-tagged c-RAF (306 to 648 residues) Y340D/Y341D mutant expressed in baculovirus expression system using recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468563(CHEMBL4276699)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468558(CHEMBL4286889)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468557(CHEMBL4294787)
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468567(CHEMBL4287092)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468561(CHEMBL4280550)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468570(CHEMBL4290513)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of recombinant human GST-tagged c-RAF (306 to 648 residues) Y340D/Y341D mutant expressed in baculovirus expression system using recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468570(CHEMBL4290513)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468572(CHEMBL4279170)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468567(CHEMBL4287092)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468571(CHEMBL4287349)
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468559(CHEMBL4281642)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468571(CHEMBL4287349)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468562(CHEMBL4292278)
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468559(CHEMBL4281642)
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468562(CHEMBL4292278)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468569(CHEMBL4283993)
Affinity DataIC50: 5.72E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468558(CHEMBL4286889)
Affinity DataIC50: 7.83E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468568(CHEMBL4291854)
Affinity DataIC50: 8.43E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468557(CHEMBL4294787)
Affinity DataIC50: 8.89E+4nMAssay Description:Inhibition of N-terminal flag-tagged JNK1 (unknown origin) expressed in baculovirus expression system after 60 mins in presence of [gamma-32P]ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468570(CHEMBL4290513)
Affinity DataIC50: 9.36E+4nMAssay Description:Inhibition of N-terminal flag-tagged JNK1 (unknown origin) expressed in baculovirus expression system after 60 mins in presence of [gamma-32P]ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468566(CHEMBL4285067)
Affinity DataIC50: 9.59E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468564(CHEMBL4288433)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468560(CHEMBL4282640)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468568(CHEMBL4291854)
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50468557(CHEMBL4294787)
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibition of MEK1/2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50468570(CHEMBL4290513)
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of MEK1/2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50468565(CHEMBL4277125)
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibition of MEK1/2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468561(CHEMBL4280550)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468570(CHEMBL4290513)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal flag-tagged p38alpha (unknown origin) expressed in baculovirus expression system using MBP as substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468564(CHEMBL4288433)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468565(CHEMBL4277125)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468557(CHEMBL4294787)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal flag-tagged p38alpha (unknown origin) expressed in baculovirus expression system using MBP as substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468565(CHEMBL4277125)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal flag-tagged p38alpha (unknown origin) expressed in baculovirus expression system using MBP as substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468565(CHEMBL4277125)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged c-RAF (306 to 648 residues) Y340D/Y341D mutant expressed in baculovirus expression system using recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468569(CHEMBL4283993)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468566(CHEMBL4285067)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468565(CHEMBL4277125)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal flag-tagged JNK1 (unknown origin) expressed in baculovirus expression system after 60 mins in presence of [gamma-32P]ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468563(CHEMBL4276699)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468560(CHEMBL4282640)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed