Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50001269
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274369(CHEMBL4126267)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274344(CHEMBL4129184)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274346(CHEMBL4129491)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274400(CHEMBL4128213)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274345(CHEMBL4130242)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274371(CHEMBL4128106)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274365(CHEMBL4127637)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274415(CHEMBL4126833)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274322(CHEMBL4126038)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274321(CHEMBL4127346)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM86478(A-317491)
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274372(CHEMBL4127133)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274416(CHEMBL4126971)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274363(CHEMBL4127788)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274370(CHEMBL4129357)
Affinity DataIC50: 135nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274399(CHEMBL4129031)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274396(CHEMBL4130133)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274323(CHEMBL4127171)
Affinity DataIC50: 360nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274320(CHEMBL4129977)
Affinity DataIC50: 370nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274381(CHEMBL4127905)
Affinity DataIC50: 560nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274397(CHEMBL4129705)
Affinity DataIC50: 1.02E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274380(CHEMBL4126274)
Affinity DataIC50: 1.37E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274376(CHEMBL4129638)
Affinity DataIC50: 3.28E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274362(CHEMBL4128222)
Affinity DataIC50: 3.93E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274378(CHEMBL4127573)
Affinity DataIC50: 4.24E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 2/3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274365(CHEMBL4127637)
Affinity DataIC50: 4.32E+3nMAssay Description:Antagonist activity at P2X2/3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274343(CHEMBL1456917)
Affinity DataIC50: 4.79E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274375(CHEMBL4128051)
Affinity DataIC50: 5.92E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274379(CHEMBL4129448)
Affinity DataIC50: 9.80E+3nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274377(CHEMBL4126198)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274374(CHEMBL4128559)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274324(CHEMBL4129722)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274382(CHEMBL4128476)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274327(CHEMBL4126976)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274365(CHEMBL4127637)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274398(CHEMBL4125741)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274365(CHEMBL4127637)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274365(CHEMBL4127637)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274342(CHEMBL4129182)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X3 receptor expressed in C6-BU-1 cells assessed as inhibition of calcium flux after 1 hr by Fluo-3AM dye based FLIPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50274365(CHEMBL4127637)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at P2X4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed