Compile Data Set for Download or QSAR
Report error Found 91 Enz. Inhib. hit(s) with all data for entry = 50001855
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50160434(AM630 | (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-...)
Affinity DataEC50:  167nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataEC50:  237nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408215(CHEMBL4175177)
Affinity DataEC50:  96nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  229nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataEC50:  182nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408214(CHEMBL4163852)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataEC50:  687nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataIC50: 70nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataIC50: 530nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408215(CHEMBL4175177)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408214(CHEMBL4163852)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408217(CHEMBL4173284)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408214(CHEMBL4163852)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408227(CHEMBL4171735)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408221(CHEMBL4167222)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408223(CHEMBL4159313)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408222(CHEMBL4174442)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408218(CHEMBL4163771)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408223(CHEMBL4159313)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408217(CHEMBL4173284)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408227(CHEMBL4171735)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408215(CHEMBL4175177)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408227(CHEMBL4171735)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408217(CHEMBL4173284)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408221(CHEMBL4167222)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50408223(CHEMBL4159313)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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