Compile Data Set for Download or QSAR
Report error Found 94 Enz. Inhib. hit(s) with all data for entry = 50001843
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406688(CHEMBL4166620)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as inward channel current amplitude at -70 mV holding potential by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406688(CHEMBL4166620)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in rat GH4C1 cells assessed as inward channel current amplitude at -70 mV holding potential by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406539(CHEMBL4175573)
Affinity DataEC50:  2.90E+3nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in rat GH4C1 cells assessed as inward channel current amplitude at -70 mV holding potential by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406539(CHEMBL4175573)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as inward channel current amplitude at -70 mV holding potential by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50216315((1R,4R)-2-(6-chloro-3-pyridinyl)-2,5-diazabicyclo[...)
Affinity DataKi:  0.0180nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406803(CHEMBL4168511)
Affinity DataKi:  0.0200nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406472(CHEMBL4163848)
Affinity DataKi:  0.0225nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  0.0450nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406539(CHEMBL4175573)
Affinity DataKi:  0.0598nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406641(CHEMBL4170527)
Affinity DataKi:  0.0807nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406500(CHEMBL4166573)
Affinity DataKi:  0.0910nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406544(CHEMBL4174940)
Affinity DataKi:  0.118nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406515(CHEMBL4161931)
Affinity DataKi:  0.124nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406685(CHEMBL4164252)
Affinity DataKi:  0.148nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406542(CHEMBL4160595)
Affinity DataKi:  0.150nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406792(CHEMBL4174509)
Affinity DataKi:  0.342nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406686(CHEMBL4167298)
Affinity DataKi:  0.373nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406543(CHEMBL4169986)
Affinity DataKi:  0.400nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406541(CHEMBL4163257)
Affinity DataKi:  0.569nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406472(CHEMBL4163848)
Affinity DataKi:  0.684nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406641(CHEMBL4170527)
Affinity DataKi:  0.799nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406541(CHEMBL4163257)
Affinity DataKi:  0.818nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406804(CHEMBL4177192)
Affinity DataKi:  0.950nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406792(CHEMBL4174509)
Affinity DataKi:  0.988nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406686(CHEMBL4167298)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406544(CHEMBL4174940)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406500(CHEMBL4166573)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406793(CHEMBL4168267)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406685(CHEMBL4164252)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406688(CHEMBL4166620)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406794(CHEMBL4176763)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406539(CHEMBL4175573)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406704(CHEMBL4160411)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406538(CHEMBL4171125)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406540(CHEMBL4177240)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406798(CHEMBL4177261)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406797(CHEMBL4166578)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50455433(CHEMBL129801)
Affinity DataKi:  4.10nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406704(CHEMBL4160411)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406705(CHEMBL4167459)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406537(CHEMBL4171667)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406687(CHEMBL4164706)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406687(CHEMBL4164706)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406540(CHEMBL4177240)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406688(CHEMBL4166620)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406641(CHEMBL4170527)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406799(CHEMBL4175109)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Istituto Di Chimica Biomolecolare

Curated by ChEMBL
LigandPNGBDBM50406538(CHEMBL4171125)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
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