Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50002250
TargetAurora kinase A(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456107(CHEMBL4204878)
Affinity DataKd:  100nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKd:  0.501nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456108(CHEMBL4216458)
Affinity DataKd:  32nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456109(CHEMBL4212119)
Affinity DataKd:  1nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456108(CHEMBL4216458)
Affinity DataKd:  40nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456110(CHEMBL4216563)
Affinity DataKd:  5.01E+3nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456111(CHEMBL4217093)
Affinity DataKd:  50nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456107(CHEMBL4204878)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456111(CHEMBL4217093)
Affinity DataKd:  4nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456110(CHEMBL4216563)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456109(CHEMBL4212119)
Affinity DataKd:  25nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456109(CHEMBL4212119)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at C-terminal PK-fused human full length TrkA assessed as inhibition of betaNGF-induced protein binding to Shc1-EA by beta-galact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456110(CHEMBL4216563)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at C-terminal PK-fused human full length TrkA assessed as inhibition of betaNGF-induced protein binding to Shc1-EA by beta-galact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed