Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50002071
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50453074(CHEMBL4215958)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50453077(CHEMBL4216478)
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50453073(CHEMBL4204282)
Affinity DataIC50: 7.10nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50453076(CHEMBL4211510)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50453068(CHEMBL4206276)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50453070(CHEMBL4208614)
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50453072(CHEMBL4207504)
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]NMS from muscarinic receptor in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M1 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M5 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M2 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M4 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M3 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50374004(CHEMBL271108)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M1 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50374004(CHEMBL271108)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M4 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50374004(CHEMBL271108)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M2 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50374004(CHEMBL271108)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M3 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Rat)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50374004(CHEMBL271108)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]NMS from muscarinic receptor M5 in Sprague-Dawley rat brain homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed