Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50002647
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataKd: >1.00E+4nMAssay Description:Activity at PPARgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused to the PPARgamm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataKd: >1.00E+4nMAssay Description:Activity at VDR expressed in human HeLa-derived HDLN6 cells assessed as inhibition of transcriptional activity after 18 hrs by luminescence-based luc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataKd: >1.00E+4nMAssay Description:Activity at LXRbeta (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused to the LXRbeta li...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461084(CHEMBL4225088)
Affinity DataIC50: 17nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataIC50: 17nMAssay Description:Inverse agonist activity at RORgamma in human CD4+ T cells assessed as inhibition of antiCD-28 antibody stimulated IL-17A production after 4 days by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM419139(N-(4-ethylphenyl)-N- isobutyl-3- methanesulfonoxim...)
Affinity DataIC50: 20nMAssay Description:Inverse agonist activity at RORgamma in human CD4+ T cells assessed as inhibition of antiCD-28 antibody stimulated IL-17A production after 4 days by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataIC50: 26nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461074(CHEMBL4227729 | US10457637, Compound 52)
Affinity DataIC50: 30nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461075(CHEMBL4225072 | US10457637, Compound 55)
Affinity DataIC50: 34nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461086(CHEMBL4228152)
Affinity DataIC50: 39nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461083(CHEMBL4225889 | US10457637, Compound 62)
Affinity DataIC50: 44nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM419139(N-(4-ethylphenyl)-N- isobutyl-3- methanesulfonoxim...)
Affinity DataIC50: 45nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461085(CHEMBL4228331)
Affinity DataIC50: 47nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461066(CHEMBL4228566 | US10457637, Compound 53)
Affinity DataIC50: 68nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461064(CHEMBL4228932)
Affinity DataIC50: 71nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461065(CHEMBL4225020 | US10457637, Compound 18)
Affinity DataIC50: 81nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461076(CHEMBL4227214 | US10457637, Compound 124)
Affinity DataIC50: 86nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461069(CHEMBL4228522 | US10457637, Compound 66)
Affinity DataIC50: 89nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461067(CHEMBL4224870)
Affinity DataIC50: 97nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461068(CHEMBL4228069 | US10457637, Compound 24)
Affinity DataIC50: 210nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461087(CHEMBL4226731 | US10457637, Compound 92)
Affinity DataIC50: 220nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461070(CHEMBL4227173 | US10457637, Compound 2)
Affinity DataIC50: 290nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461088(CHEMBL4227798 | US10457637, Compound 81)
Affinity DataIC50: 320nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461080(CHEMBL4226601)
Affinity DataIC50: 390nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461079(CHEMBL4227543 | US10457637, Compound 65)
Affinity DataIC50: 490nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461082(CHEMBL4226691 | US10457637, Compound 63)
Affinity DataIC50: 610nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461077(CHEMBL4228981 | US10457637, Compound 60)
Affinity DataIC50: 690nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461081(CHEMBL4228045 | US10457637, Compound 42)
Affinity DataIC50: 1.10E+3nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461071(CHEMBL4227783)
Affinity DataIC50: 2.30E+3nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461073(CHEMBL4226140 | US10457637, Compound 48)
Affinity DataIC50: 6.40E+3nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-alpha(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at RORalpha (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461072(CHEMBL4227463 | US10457637, Compound 47)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor ROR-alpha(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM419139(N-(4-ethylphenyl)-N- isobutyl-3- methanesulfonoxim...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at RORalpha (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at RARgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed