Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50000622
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255775(CHEMBL4079080)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHOK1 cells assessed as induction of cAMP after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255776(CHEMBL4075310)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255775(CHEMBL4079080)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255806(CHEMBL4097100)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255777(CHEMBL4061795)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255777(CHEMBL4061795)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255805(CHEMBL4086931)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255786(CHEMBL4076777)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255814(CHEMBL4059563)
Affinity DataIC50: 132nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255813(CHEMBL4092367)
Affinity DataIC50: 242nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255808(CHEMBL4068209)
Affinity DataIC50: 354nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255787(CHEMBL4104811)
Affinity DataIC50: 445nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255810(CHEMBL4081518)
Affinity DataIC50: 582nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255807(CHEMBL4089392)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human MAGL using fluorogenic-7HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255787(CHEMBL4104811)
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255805(CHEMBL4086931)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255808(CHEMBL4068209)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255775(CHEMBL4079080)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255786(CHEMBL4076777)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255776(CHEMBL4075310)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255810(CHEMBL4081518)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255806(CHEMBL4097100)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255813(CHEMBL4092367)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255807(CHEMBL4089392)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255814(CHEMBL4059563)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human FAAH using fluorogenic arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed
LigandPNGBDBM50255775(CHEMBL4079080)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2019
Entry Details Article
PubMed