Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50002220
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to human fluorescence labelled FPRCK-alpha thrombin by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to wild-type thrombin (unknown origin) by intrinsic fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human fluorescence labelled FPRCK-alpha thrombin by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in absence of exosite 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in absence of exosite 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455303(CHEMBL4218956)
Affinity DataIC50: 1.30E+3nMAssay Description:Partial allosteric inhibition of human thrombin using S-23666 as substrate measured after 1 min by fibrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 30 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 15 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 1.80E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in absence of exosite 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in absence of exosite 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455292(CHEMBL4215598)
Affinity DataIC50: 2.00E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455293(CHEMBL4208688)
Affinity DataIC50: 2.30E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 50 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 5 uM exo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455285(CHEMBL4207062)
Affinity DataIC50: 2.60E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455291(CHEMBL4214824)
Affinity DataIC50: 2.60E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455294(CHEMBL4203810)
Affinity DataIC50: 2.60E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 10 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 5 uM exo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 20 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 30 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455297(CHEMBL4218791)
Affinity DataIC50: 3.20E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 10 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455308(CHEMBL4203401)
Affinity DataIC50: 3.30E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 20 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 15 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455289(CHEMBL4212514)
Affinity DataIC50: 3.60E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455295(CHEMBL4214371)
Affinity DataIC50: 3.80E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455307(CHEMBL4215073)
Affinity DataIC50: 4.00E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455296(CHEMBL4202710)
Affinity DataIC50: 4.90E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455309(CHEMBL4214712)
Affinity DataIC50: 8.70E+3nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455287(CHEMBL4206540)
Affinity DataIC50: 1.40E+4nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455284(CHEMBL4210645)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition measured in presence of 50 uM ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455313(CHEMBL4217251)
Affinity DataIC50: 1.30E+5nMAssay Description:Partial allosteric inhibition of human thrombin using S-23666 as substrate measured after 1 min by fibrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455290(CHEMBL4218199)
Affinity DataIC50: 1.34E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455298(CHEMBL4208441)
Affinity DataIC50: 1.34E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455302(CHEMBL4214557)
Affinity DataIC50: 1.68E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455312(CHEMBL4217769)
Affinity DataIC50: 2.29E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455304(CHEMBL4209061)
Affinity DataIC50: 3.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455310(CHEMBL4211424)
Affinity DataIC50: 3.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455288(CHEMBL4218970)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455306(CHEMBL4202894)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455305(CHEMBL4204101)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455311(CHEMBL4212825)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455299(CHEMBL4203558)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455286(CHEMBL4207916)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455300(CHEMBL4215768)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50455301(CHEMBL4207245)
Affinity DataIC50: 5.00E+5nMAssay Description:Partial allosteric inhibition of human thrombin using spectrozyme TH as substrate pretreated for 10 mins followed by substrate addition by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50350218(CHEMBL1812005)
Affinity DataIC50: 5.20E+5nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed