Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50001683
TargetCholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295320(CHEMBL4167524)
Affinity DataIC50: 27nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295319(CHEMBL4174729)
Affinity DataIC50: 210nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295326(CHEMBL4159609)
Affinity DataIC50: 290nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295327(CHEMBL4175175)
Affinity DataIC50: 470nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295317(CHEMBL4164078)
Affinity DataIC50: 610nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295323(CHEMBL4164540)
Affinity DataIC50: 890nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295321(CHEMBL4159640)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295324(CHEMBL4177242)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295322(CHEMBL4167973)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295325(CHEMBL4169394)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jiangxi University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50295320(CHEMBL4167524)
Affinity DataKi:  37nMAssay Description:Competitive inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMed