Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50001668
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50130915(CHEMBL1231178 | CHEBI:3122)
Affinity DataIC50: 210nMAssay Description:Inhibition of CE1 in human liver microsomes using D-Luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50291962(CHEMBL4174080)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50017698(cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50291961(CHEBI:69300 | paecilocin A)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50291961(CHEBI:69300 | paecilocin A)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CE1 in human liver microsomes using D-Luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50291962(CHEMBL4174080)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CE1 in human liver microsomes using D-Luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50291962(CHEMBL4174080)
Affinity DataKi:  2.34E+3nMAssay Description:Competitive inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed