Compile Data Set for Download or QSAR
Report error Found 98 Enz. Inhib. hit(s) with all data for entry = 50000451
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250584(CHEMBL4090684)
Affinity DataEC50:  178nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250580(CHEMBL4088516)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50:  128nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134946(H-Tyr-Val-Nle-Gly-His-D-Nal(2')-Arg-Trp-Asp-Arg-Ph...)
Affinity DataEC50:  630nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250587(CHEMBL4079302)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250580(CHEMBL4088516)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250591(CHEMBL4072387)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250585(CHEMBL4104092)
Affinity DataEC50:  65nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50026883(CHEMBL437050)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250587(CHEMBL4079302)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250584(CHEMBL4090684)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250591(CHEMBL4072387)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50268806(Ac-Tyr-Val-Nle-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gl...)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50026883(CHEMBL437050)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250588(CHEMBL4103570)
Affinity DataEC50: >1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250581(CHEMBL4068475)
Affinity DataEC50:  604nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250591(CHEMBL4072387)
Affinity DataEC50:  2.10nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  0.200nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250585(CHEMBL4104092)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250583(CHEMBL4089770)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50268806(Ac-Tyr-Val-Nle-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gl...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250580(CHEMBL4088516)
Affinity DataEC50:  71nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250585(CHEMBL4104092)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250591(CHEMBL4072387)
Affinity DataEC50:  0.700nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250587(CHEMBL4079302)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250583(CHEMBL4089770)
Affinity DataEC50:  444nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50268806(Ac-Tyr-Val-Nle-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gl...)
Affinity DataEC50:  1.40nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134946(H-Tyr-Val-Nle-Gly-His-D-Nal(2')-Arg-Trp-Asp-Arg-Ph...)
Affinity DataEC50:  3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134946(H-Tyr-Val-Nle-Gly-His-D-Nal(2')-Arg-Trp-Asp-Arg-Ph...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250587(CHEMBL4079302)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250584(CHEMBL4090684)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250585(CHEMBL4104092)
Affinity DataEC50:  520nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  0.0100nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50268806(Ac-Tyr-Val-Nle-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gl...)
Affinity DataEC50:  1.5nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50:  521nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250583(CHEMBL4089770)
Affinity DataEC50:  31nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50026883(CHEMBL437050)
Affinity DataEC50:  710nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50026883(CHEMBL437050)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataIC50: 0.0100nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50134946(H-Tyr-Val-Nle-Gly-His-D-Nal(2')-Arg-Trp-Asp-Arg-Ph...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250586(CHEMBL4093140)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250591(CHEMBL4072387)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250589(CHEMBL4060000)
Affinity DataIC50: 0.420nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2019
Entry Details Article
PubMed
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