Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50001422
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 23nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50: 27nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279039(CHEMBL4177185)
Affinity DataIC50: 28nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279036(CHEMBL4162061)
Affinity DataIC50: 33nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279034(CHEMBL4172740)
Affinity DataIC50: 34nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279035(CHEMBL4165597)
Affinity DataIC50: 38nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279023(CHEMBL4176892)
Affinity DataIC50: 41nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279038(CHEMBL4169030)
Affinity DataIC50: 44nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 48nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279040(CHEMBL4161755)
Affinity DataIC50: 50nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50: 56nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279039(CHEMBL4177185)
Affinity DataIC50: 79nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279036(CHEMBL4162061)
Affinity DataIC50: 93nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279034(CHEMBL4172740)
Affinity DataIC50: 104nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279035(CHEMBL4165597)
Affinity DataIC50: 116nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279023(CHEMBL4176892)
Affinity DataIC50: 128nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279038(CHEMBL4169030)
Affinity DataIC50: 132nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 132nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279040(CHEMBL4161755)
Affinity DataIC50: 141nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 230nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50: 280nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279039(CHEMBL4177185)
Affinity DataIC50: 340nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279036(CHEMBL4162061)
Affinity DataIC50: 580nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279034(CHEMBL4172740)
Affinity DataIC50: 790nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279035(CHEMBL4165597)
Affinity DataIC50: 810nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279023(CHEMBL4176892)
Affinity DataIC50: 880nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279038(CHEMBL4169030)
Affinity DataIC50: 910nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279040(CHEMBL4161755)
Affinity DataIC50: 970nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human COX-2 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279039(CHEMBL4177185)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279036(CHEMBL4162061)
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279034(CHEMBL4172740)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279035(CHEMBL4165597)
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279023(CHEMBL4176892)
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279038(CHEMBL4169030)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Damanhour University

Curated by ChEMBL
LigandPNGBDBM50279040(CHEMBL4161755)
Affinity DataIC50: 2.01E+5nMAssay Description:Inhibition of human COX-1 using [14C]-arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed