Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50000127
TargetLegumain(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240930(CHEMBL4093898)
Affinity DataIC50: 160nMAssay Description:Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetLegumain(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240931(CHEMBL4074941)
Affinity DataIC50: 170nMAssay Description:Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetLegumain(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 180nMAssay Description:Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetLegumain(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240928(CHEMBL4067280)
Affinity DataIC50: 370nMAssay Description:Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-3(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240928(CHEMBL4067280)
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of caspase-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-8(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240928(CHEMBL4067280)
Affinity DataIC50: 7.61E+4nMAssay Description:Inhibition of caspase-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-3(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of caspase-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCathepsin S(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240931(CHEMBL4074941)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cathepsin-S (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-3(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240930(CHEMBL4093898)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of caspase-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-3(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240931(CHEMBL4074941)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of caspase-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-8(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of caspase-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-8(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240930(CHEMBL4093898)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of caspase-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-8(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240931(CHEMBL4074941)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of caspase-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCathepsin S(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240930(CHEMBL4093898)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cathepsin-S (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCathepsin S(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cathepsin-S (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCathepsin S(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240928(CHEMBL4067280)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cathepsin-S (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetLegumain(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240928(CHEMBL4067280)
Affinity DataKi:  105nMAssay Description:Competitive inhibition of AEP (unknown origin) using varying levels of Z-AAN-AMC substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed