Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50002306
LigandPNGBDBM50456923(CHEMBL4213353)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50341493(Ethyl 6-(5-(Phenylsulfonamido)pyridin-3-yl)imidazo...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50456924(CHEMBL4207685)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50456925(CHEMBL4207150)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50456924(CHEMBL4207685)
Affinity DataIC50: 37nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50456923(CHEMBL4213353)
Affinity DataIC50: 45nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50341493(Ethyl 6-(5-(Phenylsulfonamido)pyridin-3-yl)imidazo...)
Affinity DataIC50: 59nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50456925(CHEMBL4207150)
Affinity DataIC50: 69nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50341493(Ethyl 6-(5-(Phenylsulfonamido)pyridin-3-yl)imidazo...)
Affinity DataIC50: 87nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50456923(CHEMBL4213353)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50456923(CHEMBL4213353)
Affinity DataIC50: 93nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50456924(CHEMBL4207685)
Affinity DataIC50: 101nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50341493(Ethyl 6-(5-(Phenylsulfonamido)pyridin-3-yl)imidazo...)
Affinity DataIC50: 104nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50456924(CHEMBL4207685)
Affinity DataIC50: 106nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50456925(CHEMBL4207150)
Affinity DataIC50: 108nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate by HTRF colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50456925(CHEMBL4207150)
Affinity DataIC50: 116nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed