Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50000310
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Iota Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14779(ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate | Pyr...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of human PDE4D catalytic domain using [3H]-cAMP as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed
LigandPNGBDBM50335099(4-chlorobenzo[d]thiazol-2-amine | CHEMBL1413383 | ...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of N-terminal 6xHis-tagged PDE10A (unknown origin) expressed in BL21 (DE3) RIL cells using 3',5'-cGMP as substrate by microcalorimetric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)