Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50000809
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260843(CHEMBL4075349)
Affinity DataKi:  48nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260844(CHEMBL4088218)
Affinity DataKi:  80nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50331291((+/-)-3-(4-Phenylbutyl)-2,3,4,5-tetrahydro-1H-3-be...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260842(CHEMBL4065052)
Affinity DataKi:  122nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260843(CHEMBL4075349)
Affinity DataKi:  157nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50331293(7-methoxy-3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  182nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50331291((+/-)-3-(4-Phenylbutyl)-2,3,4,5-tetrahydro-1H-3-be...)
Affinity DataKi:  194nMAssay Description:Displacement of [3H](+)-Pentazocine from sigma 1 receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260842(CHEMBL4065052)
Affinity DataKi:  472nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50260844(CHEMBL4088218)
Affinity DataKi:  606nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50331293(7-methoxy-3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataKi:  706nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed