Compile Data Set for Download or QSAR
Report error Found 92 Enz. Inhib. hit(s) with all data for entry = 50018703
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611758(CHEMBL5273533)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611757(CHEMBL5284762)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611757(CHEMBL5284762)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611758(CHEMBL5273533)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611757(CHEMBL5284762)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098427(CHEMBL3593591)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611756(CHEMBL5267452)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611758(CHEMBL5273533)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611752(CHEMBL5268959)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098427(CHEMBL3593591)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611753(CHEMBL5278895)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611750(CHEMBL5284080)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611756(CHEMBL5267452)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611759(CHEMBL5271864)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098427(CHEMBL3593591)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611752(CHEMBL5268959)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611758(CHEMBL5273533)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611752(CHEMBL5268959)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611758(CHEMBL5273533)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611754(CHEMBL5276916)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611753(CHEMBL5278895)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611759(CHEMBL5271864)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098426(CHEMBL3593592)
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611751(CHEMBL5268710)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611750(CHEMBL5284080)
Affinity DataIC50: 7nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611749(CHEMBL5288765)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098426(CHEMBL3593592)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611754(CHEMBL5276916)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611753(CHEMBL5278895)
Affinity DataIC50: 9nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611754(CHEMBL5276916)
Affinity DataIC50: 11nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611751(CHEMBL5268710)
Affinity DataIC50: 12nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611750(CHEMBL5284080)
Affinity DataIC50: 13nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611749(CHEMBL5288765)
Affinity DataIC50: 15nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611751(CHEMBL5268710)
Affinity DataIC50: 19nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50098426(CHEMBL3593592)
Affinity DataIC50: 29nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611749(CHEMBL5288765)
Affinity DataIC50: 58nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611760(CHEMBL5275601)
Affinity DataIC50: 200nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611760(CHEMBL5275601)
Affinity DataIC50: 390nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAurora kinase C(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of AURC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611758(CHEMBL5273533)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50611755(CHEMBL5281283)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BMPR1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
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