Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50001344
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of recombinant human full length VEGFR2 using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human full length c-MET using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant human full length KIT using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human full length RET using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length AXL using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full length FLT3 using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human full length TIE2 using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276855(CHEMBL4168618)
Affinity DataIC50: 68nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276855(CHEMBL4168618)
Affinity DataIC50: 124nMAssay Description:Inhibition of recombinant human full length FLT3 using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276846(CHEMBL4176824)
Affinity DataIC50: 442nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276845(CHEMBL4164791)
Affinity DataIC50: 809nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276853(CHEMBL4160311)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276854(CHEMBL4168226)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276851(CHEMBL4167248)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276850(CHEMBL4173099)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276852(CHEMBL4162881)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276843(CHEMBL4164843)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276847(CHEMBL4161698)
Affinity DataIC50: 8.86E+3nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276857(CHEMBL4161379)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276848(CHEMBL4166206)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276844(CHEMBL4165198)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276849(CHEMBL4173469)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276856(CHEMBL4163204)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276842(CHEMBL4167104)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed