Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50000684
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258206(CHEMBL4074532)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258188(CHEMBL4060916)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23556(N-(3-chlorophenyl)-6-methyl-2-oxo-2H-chromene-3-ca...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258214(CHEMBL4076698)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23559(6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258174(CHEMBL4080704)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258208(CHEMBL4078090)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23557(N-(4-chlorophenyl)-6-methyl-2-oxo-2H-chromene-3-ca...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23560(6-methyl-N-(4-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23538(6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258178(CHEMBL4094520)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258176(CHEMBL4089520)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258215(CHEMBL4099648)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258177(CHEMBL4073128)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258202(CHEMBL4072004)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM19187(CHEMBL396778 | (2S)-2-[({4-[(3-fluorophenyl)methox...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258211(CHEMBL4070614)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258213(CHEMBL4074339)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258199(CHEMBL4081233)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258170(CHEMBL1598233)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258210(CHEMBL4089098)
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258212(CHEMBL4085981)
Affinity DataIC50: 114nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258195(CHEMBL4099251)
Affinity DataIC50: 152nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258207(CHEMBL4075920)
Affinity DataIC50: 211nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258175(CHEMBL4081648)
Affinity DataIC50: 229nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258201(CHEMBL4091517)
Affinity DataIC50: 513nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258169(CHEMBL4097014)
Affinity DataIC50: 622nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258209(CHEMBL4102366)
Affinity DataIC50: 674nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 6.87E+4nMAssay Description:Inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23556(N-(3-chlorophenyl)-6-methyl-2-oxo-2H-chromene-3-ca...)
Affinity DataKi:  1.20nMAssay Description:Noncompetitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50258188(CHEMBL4060916)
Affinity DataKi:  2.70nMAssay Description:Noncompetitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed