Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50000657
TargetSerine/threonine-protein kinase RIO2(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)
Affinity DataKd:  7.40E+3nMAssay Description:Inhibition of partial length human RIOK2 expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)
Affinity DataKd:  1.30E+3nMAssay Description:Inhibition of partial length human MEK5 expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50133870(CHEMBL3188386 | CHEBI:78030 | US10251893, Compound...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257135(CHEMBL4080208)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257143(CHEMBL4080021)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257160(CHEMBL4096728)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50133866(CHEMBL3633802)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257141(CHEMBL4069295)
Affinity DataIC50: 6nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257139(CHEMBL4104447)
Affinity DataIC50: 8nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257144(CHEMBL4066589)
Affinity DataIC50: 9nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257142(CHEMBL4096529)
Affinity DataIC50: 11nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257145(CHEMBL4095609)
Affinity DataIC50: 11nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257138(CHEMBL4066796)
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257157(CHEMBL4103356)
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257137(CHEMBL4094309)
Affinity DataIC50: 15nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257136(CHEMBL4061069)
Affinity DataIC50: 15nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257134(CHEMBL4066798)
Affinity DataIC50: 24nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257161(CHEMBL4075204)
Affinity DataIC50: 29nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257158(CHEMBL4104257)
Affinity DataIC50: 29nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257162(CHEMBL4102043)
Affinity DataIC50: 42nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257129(CHEMBL4088085)
Affinity DataIC50: 60nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257159(CHEMBL4086549)
Affinity DataIC50: 67nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257140(CHEMBL4078705)
Affinity DataIC50: 72nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257137(CHEMBL4094309)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257158(CHEMBL4104257)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257144(CHEMBL4066589)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257157(CHEMBL4103356)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257145(CHEMBL4095609)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257145(CHEMBL4095609)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257137(CHEMBL4094309)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257158(CHEMBL4104257)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257161(CHEMBL4075204)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257157(CHEMBL4103356)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257161(CHEMBL4075204)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257144(CHEMBL4066589)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed