Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50001058
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataEC50:  253nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity measured after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 measured after 48 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 measured after 48 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 2.5 uM measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268587(CHEMBL3356782)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268599(CHEMBL4078066)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 1 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268598(CHEMBL4064416)
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 6.32E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268577(CHEMBL4092147)
Affinity DataIC50: 6.93E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268580(CHEMBL4074079)
Affinity DataIC50: 7.65E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268578(CHEMBL4065461)
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 8.28E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268600(CHEMBL4102336)
Affinity DataIC50: 8.29E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268579(CHEMBL4100840)
Affinity DataIC50: 8.38E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268576(CHEMBL4071352)
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 measured after 48 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268581(CHEMBL4075139)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 0.5 uM measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 0.25 uM measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268593(CHEMBL4085950)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268575(CHEMBL4093700)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268602(CHEMBL4073000)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268561(CHEMBL4083430)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268591(CHEMBL4082474)
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268592(CHEMBL4060585)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 treated for 48 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268601(CHEMBL4101419)
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 0.1 uM measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 0.05 uM measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268560(CHEMBL4093128)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 0.025 uM measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 9.69E+4nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed