Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50001038
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268191(CHEMBL4102765)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268184(CHEMBL4060026)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268190(CHEMBL4099888)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268187(CHEMBL4104323)
Affinity DataIC50: 5.57E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268185(CHEMBL4088260)
Affinity DataIC50: 6.45E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268189(CHEMBL4081883)
Affinity DataIC50: 8.92E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268172(CHEMBL4061636)
Affinity DataIC50: 9.91E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268188(CHEMBL4089751)
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268186(CHEMBL4089711)
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268173(CHEMBL4069708)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50268192(CHEMBL4086302)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed